Pertautan Penambat (Anchoring Junction)

Pertautan penambat (anchoring junction) merupakan pertautan yang berfungsi menambatkan sitoskeleton suatu sel ke sitoskeleton sel tetangganya atau ke matriks ekstraseluler.

Pertautan penambat (anchoring junction) paling banyak ditemukan pada jaringan-jaringan yang mendapatkan tekanan mekanis  kuat, seperti: jaringan otot jantung, epitelium kulit, dan leher rahim. Sehingga memungkinkan sel untuk tetap saling merekat atau tidak rusak.

Pertautan Sel

Pertautan penambat (anchoring junction) dibagi menjadi 3 macam pertautan, yaitu: pertautan tambat (adherens junction/zonula adherens), desmosoma, hemidesmosoma.

1) Pertautan Tambat (Adherens Junction/Zonula Adherens)

Pertautan Tambat (Adherens Junction/Zonula Adherens)

Fungsinya adalah menghubungkan filamen aktin didalam suatu sel dengan sel selanjutnya atau sel disampingnya.

 

2) Desmosoma

Desmosoma

Fungsinya adalah menghubungkan filamen intermedia didalam suatu sel ke sel selanjutnya atau sel disampingnya.

 

3) Hemidesmosoma

Hemidesmosoma

Fungsinya adalah menghubungkan filamen intermedia atau filamen aktin (mikrofilamen) suatu sel dengan matriks ekstraselulernya.

 

Catatan: hemidesmosoma  sering disebut setengah, sebagian atau separuh dari desmosoma. Hal tersebut disebabkan struktur atau bentuk dari hemidesmosoma yang menyerupai desmosoma. Hanya saja, hemidesmosoma merupakan pertautan antar sel dengan matriks ekstraseluler sehingga membuatnya hanya memiliki separuh bagian seperti yang dimiliki oleh desmosoma dan langsung tersambung ke matriks ekstraseluler.

 

Berdasarkan struktur dan fungsinya, pertautan penambat (anchoring junction) dibedakan menjadi dua, yaitu:

1) Desmosoma dan Hemidesmosoma

Merupakan  tempat pengikatan filamen intermedia dan filamen aktin (mikrofilamen).

2) Pertautan Tambat (Adherens Junction/Zonula Adherens)

Merupakan tempat pengikatan filamen aktin (mikrofilamen) dari  sel yang  satu ke sel yang lain atau dari satu tempat ke tempat lain di satu sel.

 

Berdasarkan segi molekular, pertautan penambat (anchoring junction) dibedakan menjadi dua, yaitu:

1) Protein pengikat intrasel

Menghubungkan kompleks pertautan dengan elemen sitoskelet.

2) Glikoprotein transmembran penghubung

Menghubungkan bagian yang intraselnya berikatan dengan satu atau  lebih protein pengikat intrasel, dan bagian luarnya berinteraksi dengan  matriks atau  glikoprotein transmembran dari sel lain.

 

Demikian penjelasan tentang Pertautan Penambat (Anchoring Junction). Mohon masukan berupa kritik dan saran teman-teman sekalian. Terimakasih sudah berkunjung. Semoga bermanfaat.

Berikut saya sertakan Pertautan Penambat (Anchoring Junction) dalam bentuk Power Point yang sebelumnya telah saya kumpulkan guna melengkapi tugas yang telah diberikan oleh dosen.

Tinggalkan alamat email anda dalam kolom komentar untuk memperoleh powerpoint tersebut.

Penulis: mayasandri

Hi. Aku Maya, saat ini aku berstatus sebagai mahasiswi dari Pend.Biologi FKIP Universitas Riau. Senang dapat menyapa dan dapat berbagi dengan anda

134 thoughts on “Pertautan Penambat (Anchoring Junction)”

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